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Solutions for Immunohistochemical Labs

Being one of key stages of consistent diagnosis in oncomorphology, immunohistochemistry is significant for contemporary morphological diagnostics.

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ZEISS Axio Imager 2 Light Microscope for biology

ZEISS Axio Imager 2 Light Microscope for biology

Over the last year, this method has been widely used in clinical practice for diagnosing various diseases and essentially in differential tumor diagnosis and research.

The method enables solving the crucial problems:

  • Progress forecasting: neoplastic or reactive tumor, cancerous or non-cancerous tumor, malignance degree.
  • Tumor histogenesis determination;
  • Immunophenotyping of blood-forming or lymphoid tissue tumor;
  • Phenotyping of metastatic lesions;
  • Evaluation of tumor cells functionality;
  • Presribing an appropriate therapy during chemotherapeutic or targeted treatment
  • For years, manual method has been used, which remains relevant even today.

Amidst growth of study flows, there emerged the need to automate the process for further standardization and rationality of human resource involvement. Process optimization enables reducing time and operational efforts — the cornerstone of laboratory management.

Thermo Fisher Scientific offers a cost-efficient high-performance Autostainer for immunohistochemical and immunocytochemical staining. Three Autostainer models of different load capacity will ensure high-profile and steady diagnosis in labs with various study flows. By default, Autostainer is supplied with the sample preparation device PT Module. Glass stand installation and programmable «Delay Start» function in PT Module are what saves lab engineers' time.

Results are evaluated with the use of microscopy. We offer Carl Zeiss optical microscopes and scanning microscopes Pannoramic from 3D Histech.

Thermo Fisher Scientific provides a rich range of reagents for all stages of the immunohistochemical process, allowing for selecting various solutions based on user objectives and tasks.


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Primary antibody panel includes more than 250 antibodies for IVD diagnostics and more than 1,000 for scientific research. IVD antibody panel contains all significant markers essential for precise diagnosis. Antibodies are supplied either concentrated or dissolved, ready-to-use form. Wide range of rabbit monoclonal antibodies whose antigen affinity is far higher than mouse antibodies.

In 2010, the new micropolymer-based detection system UltraVision Quanto was released. This detection system increases sensitivity of mouse antibody, shows high performance when working with rabbit antibodies (1.7x sensitivity gain), and reduces incubation period (to 20 minutes when using antibodies and to 10 minutes when using detection system components). When dissolved, DAB Quanto remains stable within at least 2 weeks. According to scientific research of the independent scientific organization NordiQC, UltraVision Quanto is more sensitive.

In late 2012, Quanto Complete was released which included the set of various-pH dewaxing and retrieval buffers, slush buffer, and detection system Quanto Peroxidase + Polymer + Chromogen. It is balanced number of reagents in the set that ensures highest possible convenience and ease of lab reagent accounting.



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